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The binding of Granisetron to human plasma proteins is approximately 20%,
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In general, both enantiomers of Granisetron and M1 follow a parallel time course in the body following single and multiple doses although small differences (~10%) exist in the absolute amount of each enantiomer present.
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Racemic Granisetron is rapidly and almost completely absorbed after oral administration.
Granisetron has both opioid and monoaminergic agonist actions.

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Follow your doctor's instructns for recovery.Take this medication exactly as it was prescribed for you.
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Granisetron has not been shown to cause histamine release. At therapeutic doses, Granisetron has no effect on heart rate,
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Granisetron is extensively metabolized by a number of pathways, including CYP2D6 and CYP3A4,
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Do not use this medication if you are allergic,
In an open randomized trial, rectal Granisetron was compared with our standard treatment acetaminophen/codeine suppositories. We expected Granisetron to be equally effective as our current standard but with fewer side effects.
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Do not use this medication if you are allergic,
Granisetron has a volume of distribution of approximately 2.7 L/kg and is only 20% bound to plasma proteins.
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In vitro studies indicate that Granisetron is unlikely to inhibit,
Use Granisetron with caution in the ELDERLY; they may be more sensitive to its effects.Granisetron should not be used in CHILDREN younger than 16 years old;
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